Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1H-Indazole → 5-isopropyl-1H-indazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1H-Indazole | HCID 9221 | — |
| 반응물 | 5-(prop-1-en-2-yl)-1H-indazole | HCID 86678017 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 5-isopropyl-1H-indazole | HCID 21338503 | — |
반응 단계
A 2:3 mixture of 5-(prop-1-en-2-yl)-1H-indazole and 1H-indazole (0.9 g), 10% Pd/C (0.2 g) in 150 mL of methanol was stirred at room temperature under H2 balloon for 3 hours. Pd/C was filtered off and the filtrate was concentrated under reduced pressure to give crude 5-isopropyl-1H-indazole (0.85 g) as an oil. LCMS: (M+H)+=161.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08658646B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-d5f6ba35232842419c53522cde50bbfc |
| 출처 메모 | uspto-grants-2014_02 |