Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thiomorpholine → 4-(3,5-Dimethoxybenzyl)thiomorpholine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thiomorpholine | HCID 67164 | — |
| 반응물 | 3,5-Dimethoxybenzyl chloride | HCID 2758395 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 4-(3,5-Dimethoxybenzyl)thiomorpholine | HCID 756021 | 73.7% |
반응 단계
Thiomorpholine (3.4 g) was added to a solution of 3,5-dimethoxybenzyl chloride (2 g) in THF (25 mL) and the mixture was stirred overnight at room temperature. The solid material was removed by filtration and the filtrate was evaporated. The residue was purified by column chromatography (silica gel; eluent: EtOAc/hexane 1/2) to yield 2 g of 3,5-dimethoxy-1-(thiomorpholino-methyl)benzene. ESMS: m/z 253 (M).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06855843B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-d8bd3fe4ea95445aa9547aebb5a6afed |
| 출처 메모 | uspto-grants-2005_02 |