Methyl 2-((3-nitrophenyl)methylene)-3-oxobutanoate → 103898-38-0

HRID 247125노트

반응식

HRID 247125 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([CH:16]=[CH:17][CH:18]=1)[CH:7]=[C:8]([C:13]([CH3:15])=O)[C:9]([O:11][CH3:12])=[O:10])([O-:3])=[O:2].[CH2:19]([C:23]1[O:27][N:26]=[C:25]([CH2:28][N:29]([CH2:31][C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[CH3:30])[N:24]=1)[C:20]([CH3:22])=O.O.[NH3:39]>C(O)(C)C>[CH3:22][C:20]1[NH:39][C:13]([CH3:15])=[C:8]([C:9]([O:11][CH3:12])=[O:10])[CH:7]([C:6]2[CH:16]=[CH:17][CH:18]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=2)[C:19]=1[C:23]1[O:27][N:26]=[C:25]([CH2:28][N:29]([CH2:31][C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[CH3:30])[N:24]=1

참가 물질

5

반응물 3

HCID 1536427Methyl 2-((3-nitrophenyl)methylene)-3-oxobutanoateHCID 12896473Azane;hydrateHCID 201612565-acetonyl-3-(N-benzyl-N-methylamino)methyl-1,2,4-oxadiazole

생성물 1

HCID 128443103898-38-0

시약·촉매·용매 1

HCID 3776Isopropanol용매

실험 절차

A mixture of 250 mg of methyl 2-(3-nitrobenzylidene)acetoacetate, 260 mg of 5-acetonyl-3-(N-benzyl-N-methylamino)methyl-1,2,4-oxadiazole, 3 ml of isopropyl alcohol and 40 mg of 29% ammonia water was reacted and worked up as described in Example 104 to give methyl 1,4-dihydro-2,6-dimetyl-3-[3-(N-benzyl-N-methylamino)methyl-1,2,4-oxadiazol-5-yl]-4-(3-nitrophenyl)pyridine-5-carboxylate, m.p. 126°-127° C.

후처리

  1. customwas reacted

출처 및 근거

ORD 기록
ord-2392f2e657514f2db6cbb02937a0862c
출처 데이터셋
uspto-grants-1987_11
특허 번호
US04705786

반응 노트

불러오는 중…