Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(3,5-Difluorophenyl)acrylic acid → 3-(3,5-Difluorophenyl)propionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(3,5-Difluorophenyl)acrylic acid | HCID 522810 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 3-(3,5-Difluorophenyl)propionic acid | HCID 3669498 | 99% |
반응 단계
A solution of 3-(3,5-difluorophenyl)propenoic acid (0.0435 mol) in tetrahydrofuran (100 ml) and a slurry of 10% palladium on carbon (1.5 g) in ethyl acetate were shaken together under 50 psi hydrogen for 4 hours. The mixture was filtered and concentrated to yield 8 g (99%) of a yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04707488 |
| 출처 데이터셋 | uspto-grants-1987_11 |
| ORD ID | ord-d9ae1a7a367840edaf522e00b5698f79 |
| 출처 메모 | uspto-grants-1987_11 |