Potassium Cyanide → 2-(4-Bromo-3-methoxyphenyl)acetonitrile

HRID 247454노트

반응식

HRID 247454 반응식
[Br:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6]Cl)=[CH:4][C:3]=1[O:10][CH3:11].[C-:12]#[N:13].[K+]>C(O)C.O>[Br:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][C:12]#[N:13])=[CH:4][C:3]=1[O:10][CH3:11]

참가 물질

5

반응물 2

HCID 9032Potassium CyanideHCID 201606681-Bromo-4-(chloromethyl)-2-methoxybenzene

생성물 1

HCID 27355842-(4-Bromo-3-methoxyphenyl)acetonitrile

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

4-Bromo-3-methoxybenzyl chloride (23.5 g, 0.1 m) dissolved in ethanol (500 ml) is treated with potassium cyanide (13 g, 0.2 m) dissolved in water. The mixture is warmed and stirred to give 4-bromo-3-methoxyphenylacetonitrile.

후처리

  1. temperatureThe mixture is warmed

출처 및 근거

ORD 기록
ord-a321e99753494a428a047e7c4d9c680f
출처 데이터셋
uspto-grants-1987_11
특허 번호
US04707483

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