Methanol → Benzeneacetic acid, alpha-ethyl-, methyl ester
반응식
[C:1]1([CH:7]([CH2:11][CH3:12])[C:8]([OH:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)(Cl)=O.[CH3:17]O>C(OCC)C>[C:1]1([CH:7]([CH2:11][CH3:12])[C:8]([O:10][CH3:17])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1참가 물질
5
실험 절차
To 102 g. of 2-phenylbutyric acid dissolved in 1 liter of methanol was added 2 ml of thionyl chloride. The solution was allowed to stand at room temperature overnight. The solvent was removed in vacuo to yield an oil which was dissolved in diethyl ether, washed successively with dilute sodium bicarbonate solution and saturated sodium chloride solution, dried over anhydrous potassium carbonate, and concentrated in vacuo. Distillation yielded 101 g of the title compound as a water-white oil, b.p. 62°-65°/0.5 mm, having the following elemental analysis:
후처리
- customThe solvent was removed in vacuo
- customto yield an oil which
- washwashed successively with dilute sodium bicarbonate solution and saturated sodium chloride solution
- dry with materialdried over anhydrous potassium carbonate
- concentrationconcentrated in vacuo
- distillationDistillation
출처 및 근거
- ORD 기록
- ord-6cb8aa009e3d4806be2a7f4eb9928fba
- 출처 데이터셋
- uspto-grants-1987_11
- 특허 번호
- US04707499
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