Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → N-(2-cycloheptenyl)dichloromaleinimide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Dichloromaleic anhydride | HCID 70728 | — |
| 반응물 | Cyclohept-2-en-1-amine | HCID 11263481 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | N-(2-cycloheptenyl)dichloromaleinimide | HCID 13578660 | 70.7% |
반응 단계
A mixture of 2-cycloheptenylamine (1.01 g), dichloromaleic anhydride (1.67 g) and acetic acid (10 ml) was heated under reflux for 3 hours. After cooling, ether (20 ml) was added to the reaction mixture which was then washed with a saturated aqueous sodium hydrogencarbonate solution, water and a saturated aqueous sodium chloride solution in this order. The organic layer was dried over anhydrous magnesium sulfate and concentrated. The deposited crystal was purified by recrystallization from hexane to obtain 1.67 g of N-(2-cycloheptenyl)dichloromaleinimide [Compound (217)].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04709052 |
| 출처 데이터셋 | uspto-grants-1987_11 |
| ORD ID | ord-abdfc592559a4f5aa99b7d586c93a409 |
| 출처 메모 | uspto-grants-1987_11 |