N-(4-Nitrophenyl)propionamide → N-(4-Aminophenyl)propanamide
반응식
[C:1]([NH:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][CH:7]=1)(=[O:4])[CH2:2][CH3:3].[H][H]>CO.[Pd]>[C:1]([NH:5][C:6]1[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][CH:7]=1)(=[O:4])[CH2:2][CH3:3]참가 물질
5
실험 절차
250 mg (2 mmol) of N-propionyl-4-nitroaniline are dissolved in 200 ml of methanol and combined with 0.6 g of 10% palladium/charcoal. The product is hydrogenated in a hydrogen atmosphere at 2 bar for 30 minutes. Then the catalyst is filtered off and the solvent is eliminated in vacuo.
후처리
- filtrationThen the catalyst is filtered off
출처 및 근거
- ORD 기록
- ord-3b91ba32e4944bce809d7a26b6f46926
- 출처 데이터셋
- uspto-grants-2005_02
- 특허 번호
- US06855710B2
반응 노트
불러오는 중…