Ethyl diazoacetate → Ethyl chrysanthemate

HRID 247732

반응식

HRID 247732 반응식
[CH3:1][C:2](=[CH:4][CH:5]=[C:6]([CH3:8])[CH3:7])[CH3:3].[N+](=[CH:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])=[N-]>C(Cl)Cl>[CH3:16][CH2:15][O:14][C:12]([CH:11]1[C:6]([CH3:8])([CH3:7])[CH:5]1[CH:4]=[C:2]([CH3:3])[CH3:1])=[O:13]

참가 물질

4

반응물 2

HCID 12192Ethyl diazoacetateHCID 12992Biisocrotyl

생성물 1

HCID 7334Ethyl chrysanthemate수율 89.6%

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

A flask was charged with CH2Cl2 (25 mL), 2,5-dimethyl-2,4-hexadiene (25 mL) and 0.45 g of the Cu,K-PFIEP[SO3H] catalyst, prepared as described above. A solution of ethyl diazoacetate (2.5 g) in CH2Cl2 (25 mL) was added slowly dropwise and the resulting reaction mixture was stirred for 24 hours at ambient temperature. Gas chromatography analysis showed that the resulting product contained cis- and trans-ethyl chrysanthemumates in a 1:1.66 isomer ratio and a combined yield of 89.6%.

후처리

  1. customprepared
  2. customthe resulting reaction mixture

출처 및 근거

ORD 기록
ord-5b3398a32e804dbd8c4f7bb4716c2929
출처 데이터셋
uspto-grants-1987_11
특허 번호
US04709085

연결된 노트

불러오는 중…