Benzoic acid, 4-((1-oxodecyl)oxy)- → 4-(1,1,1-Trifluoro-2-decyloxycarbonyl)phenyl 4-n-decanoyloxybenzoate

HRID 247785

반응식

HRID 247785 반응식
[C:1]([O:12][C:13]1[CH:21]=[CH:20][C:16]([C:17]([OH:19])=[O:18])=[CH:15][CH:14]=1)(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].O[C:23]1[CH:44]=[CH:43][C:26]([C:27]([O:29][CH:30]([CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])[C:31]([F:34])([F:33])[F:32])=[O:28])=[CH:25][CH:24]=1>O1CCCC1>[C:1]([O:12][C:13]1[CH:21]=[CH:20][C:16]([C:17]([O:19][C:23]2[CH:24]=[CH:25][C:26]([C:27]([O:29][CH:30]([CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])[C:31]([F:32])([F:33])[F:34])=[O:28])=[CH:43][CH:44]=2)=[O:18])=[CH:15][CH:14]=1)(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

참가 물질

4

반응물 2

HCID 3608562Benzoic acid, 4-((1-oxodecyl)oxy)-2회HCID 147457541,1,1-Trifluoro-2-decyl 4-hydroxybenzoate

생성물 1

HCID 190139204-(1,1,1-Trifluoro-2-decyloxycarbonyl)phenyl 4-n-decanoyloxybenzoate

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

To a solution of the 4-n-decanoyloxybenzoic acid (0.4 g) obtained in (3) and the 1,1,1-trifluoro-2-decyl 4-hydroxybenzoate (0.4 g) obtained in (2) in tetrahydrofuran (about 30 ml) were added dicyclohexylcarbodiimide (0.32 g) and dimethylaminopyridine (0.01 g). The mixture was stirred at room temperature for about 20 hours and was distilled to remove the solvent. The residue was dissolved in dichloromethane and washed with water. The organic layer was dried over anhydrous magnesium sulfate and was distilled to remove the solvent. The residue was purified by silica-gel column chromatography (a developer : hexane/ethyl acetate=20/1) to obtain the titled compound (0.15 g). Phase transition temperatures (° C.) were observed under a polarization microscope using a hot stage as follows: ##STR53## where

출처 및 근거

ORD 기록
ord-6cfe97d6e01c4c83a1905e2fa8b45e0c
출처 데이터셋
uspto-grants-1993_05
특허 번호
US05207947

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