Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Hydroxybenzoic Acid → 4-Undecanoyloxybenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Hydroxybenzoic Acid | HCID 135 | — |
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 2-Dimethylaminopyridine | HCID 21885 | — |
| 반응물 | Undecanoyl chloride | HCID 87287 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | 4-Undecanoyloxybenzoic acid | HCID 15456874 | 75.1% |
반응 단계
To a solution of p-hydroxybenzoic acid (3 g) and triethylamine (2.4 g) in dichloromethane (30 ml) were added undecanoyl chloride (4.5 g) and dimethylaminopyridine (0.2 g). The mixture was stirred at room temperature for about 20 hours. After dilute aqueous hydrochloric acid solution was added, an organic layer was separated by a funnel. After the solution was distilled to remove the solvent, the residue was washed with n-hexane and dried to obtain the titled compound (about 5 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05207947 |
| 출처 데이터셋 | uspto-grants-1993_05 |
| ORD ID | ord-95f5ab90248642f89e9fa8c60e1b1a59 |
| 출처 메모 | uspto-grants-1993_05 |