Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Hydroxybenzoic Acid → Benzoic acid, 4-((1-oxodecyl)oxy)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Hydroxybenzoic Acid | HCID 135 | — |
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 2-Dimethylaminopyridine | HCID 21885 | — |
| 반응물 | Decanoyl chloride | HCID 66982 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | Benzoic acid, 4-((1-oxodecyl)oxy)- | HCID 3608562 | 42.5% |
반응 단계
A solution of 4-hydroxybenzoic acid (3 g), decanoic acid chloride (4.3 g), triethylamine (2.4 g) and dimethylaminopyridine (0.2 g) in methylene chloride (50 ml) was stirred at room temperature for 24 hours, and then poured in water. The solution was neutralized with dilute aqueous hydrochloric acid solution and extracted with dimethyl ether. The extracted product was dried over anhydrous magnesium sulfate and distilled to remove the solvent. The residue was washed enough with hexane to obtain the titled compound (2.7 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05207947 |
| 출처 데이터셋 | uspto-grants-1993_05 |
| ORD ID | ord-081baeb5b5c44533a76afd5b27c1e8e0 |
| 출처 메모 | uspto-grants-1993_05 |