Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-Fluoro-4-n-tridecanoyloxybenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 2-Dimethylaminopyridine | HCID 21885 | — |
| 반응물 | Tridecanoyl chloride | HCID 87288 | — |
| 반응물 | 2-Fluoro-4-hydroxybenzoic Acid | HCID 2783398 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | 2-Fluoro-4-n-tridecanoyloxybenzoic acid | HCID 19365268 | 59.4% |
반응 단계
To a solution of 2-fluoro-4-hydroxybenzoic acid (1.4 g) and triethylamine (1.0 g) in dichloromethane (40 ml) were added tridecanoyl chloride (2.0 g) and dimethylaminopyridine (0.2 g). The solution was stirred at room temperature for about 20 hours and thereto was added dilute aqueous hydrochloric acid solution. The organic layer was separated by a funnel and distilled to remove the solvent. The residue was washed with n-hexane and dried to obtain the titled compound (about 1.8 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05207947 |
| 출처 데이터셋 | uspto-grants-1993_05 |
| ORD ID | ord-01c87d2080664374a114683782c76fb9 |
| 출처 메모 | uspto-grants-1993_05 |