Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-[2,6-bis(1-methylethyl)phenyl]-2-[phenylmethyl]amino-acetamide → HCID 15452514, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-[2,6-bis(1-methylethyl)phenyl]-2-[phenylmethyl]amino-acetamide | HCID 19764427 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | HCID 15452514 | HCID 15452514 | 80.2% |
반응 단계
To a solution of N-[2,6-bis(1-methylethyl)phenyl]-2-[(phenylmethyl)amino]acetamide (Example V) (0.80 g, 2.5 mmol) in methanol (10 mL) is added 20% Pd/C (0.1 g). The mixture is stirred under an atmosphere of hydrogen for 20 hours. After filtration and concentration, flash chromatography (ethyl acetate) affords 0.47 g of the title compound as a white solid; mp 88°-95° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05208224 |
| 출처 데이터셋 | uspto-grants-1993_05 |
| ORD ID | ord-54a7e6c6256c4bfead7a8a1347cd0de0 |
| 출처 메모 | uspto-grants-1993_05 |