참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Imidazole | HCID 795 | — |
| 반응물 | Ethyl orthoformate | HCID 31214 | — |
| 촉매 | p-Toluenesulfonic acid | HCID 6101 | — |
| 생성물 | 1-(diethoxymethyl)-1H-imidazole | HCID 3849535 | 72.4% |
반응 단계
Imidazole (6.81 g, 0.10 mol, 1.0 eq), triethyl orthoformate (66.5 mL, 0.40 mol, 4.0 eq) and para-toluenesulfonic acid (0.5 g) were combined and heated at 130° C. Ethanol was slowly distilled off. After the distillation of the ethanol ceased, the reaction was distilled using a floor pump (0.1 mm). Excess triethyl orthoformate distilled at 50° C. and then the product was distilled at 78°-84° C. to give the title compound (12.316 g, 72%). B. 2-Butyl-1H-imidazole
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05208235 |
|---|
| 출처 데이터셋 | uspto-grants-1993_05 |
|---|
| ORD ID | ord-06b1da150e4241318a794b79309b0d3b |
|---|
| 출처 메모 | uspto-grants-1993_05 |
|---|
