Oxalyl chloride → Benzoyl chloride, 4-(tetradecyloxy)-

HRID 247913

반응식

HRID 247913 반응식
[CH2:1]([O:15][C:16]1[CH:24]=[CH:23][C:19]([C:20](O)=[O:21])=[CH:18][CH:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].C(Cl)(=O)C([Cl:28])=O>CN(C)C=O.C(Cl)Cl>[CH2:1]([O:15][C:16]1[CH:24]=[CH:23][C:19]([C:20]([Cl:28])=[O:21])=[CH:18][CH:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

참가 물질

5

반응물 2

HCID 65578Oxalyl chlorideHCID 2894104-(Tetradecyloxy)benzoic acid

생성물 1

HCID 9998158Benzoyl chloride, 4-(tetradecyloxy)-

시약·촉매·용매 2

HCID 6228Dimethylformamide촉매HCID 6344Dichloromethane용매

실험 절차

To a room temperature suspension of 15 g of product from Example 2, 160 ml methylene chloride and 5 drops dimethylformamide is added 5.87 ml oxalyl chloride. The reaction mixture is stirred at room temperature for 18 hours, concentrated in vacuo, dissolved in 300 ml of diethyl ether, filtered through diatomaceous earth and the filtrate concentrated in vacuo to give 15.5 g of the desired product.

후처리

  1. concentrationconcentrated in vacuo
  2. dissolutiondissolved in 300 ml of diethyl ether
  3. filtrationfiltered through diatomaceous earth
  4. concentrationthe filtrate concentrated in vacuo

출처 및 근거

ORD 기록
ord-724eb1a2d07c4cb6a7e2a01dabb3dd33
출처 데이터셋
uspto-grants-1993_05
특허 번호
US05208247

연결된 노트

불러오는 중…