Protocatechuic Acid → Methyl 3,4-Dihydroxybenzoate

HRID 248008

반응식

HRID 248008 반응식
[OH:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[OH:11])[C:5]([OH:7])=[O:6].[CH3:12]O.S(=O)(=O)(O)O>O>[CH3:12][O:6][C:5](=[O:7])[C:4]1[CH:8]=[CH:9][C:10]([OH:11])=[C:2]([OH:1])[CH:3]=1

참가 물질

5

반응물 3

HCID 72Protocatechuic AcidHCID 887MethanolHCID 1118Sulfuric Acid

생성물 1

HCID 287064Methyl 3,4-Dihydroxybenzoate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of 100 g of 3,4-dihydroxy benzoic acid, 600 ml methyl alcohol and 10 ml of concentrated sulfuric acid is heated at reflux for 18 hours. The reaction mixture is cooled to room temperature, poured into water and extracted with methylene chloride. The organic layer is washed with saturated sodium bicarbonate and sodium chloride, dried and concentrated in vacuo to give 50.6 g of the desired product.

후처리

  1. temperatureis heated
  2. temperatureat reflux for 18 hours
  3. extractionextracted with methylene chloride
  4. washThe organic layer is washed with saturated sodium bicarbonate and sodium chloride
  5. customdried
  6. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-0728eac988504734b7fcf8ac9919ae17
출처 데이터셋
uspto-grants-1993_05
특허 번호
US05208247

연결된 노트

불러오는 중…