Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 3-Hexadecyloxy-2-methylenepropan-1-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | 1-Bromohexadecane | HCID 8213 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 2-Butene-1,2-diol | HCID 39605 | — |
| 생성물 | 3-Hexadecyloxy-2-methylenepropan-1-ol | HCID 11358886 | — |
반응 단계
To 18.5 g of washed sodium hydride in 500 ml of dry dimethylformamide in a water bath is added dropwise, 67.4 g of 2-butene-1,2-diol. A solution of 235 g of hexadecylbromide in 100 ml of dimethylformamide is added dropwise. This mixture is stirred at room temperature for 2 days then poured into water and extracted with ether. The ether extract is separated, dried, evaporated and purified by chromatography, to give 30 g of the desired compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05208223 |
| 출처 데이터셋 | uspto-grants-1993_05 |
| ORD ID | ord-ad49c1303dd048139ab41dea53333574 |
| 출처 메모 | uspto-grants-1993_05 |