Sodium Iodide → Isopropoxycarbonyloxyethyl iodide
반응식
[CH:1]([O:4][C:5]([O:7][CH2:8][CH2:9]Cl)=[O:6])([CH3:3])[CH3:2].[I-:11].[Na+]>[Cl-].[Zn+2].[Cl-].C(Cl)(Cl)(Cl)Cl>[CH:1]([O:4][C:5]([O:7][CH2:8][CH2:9][I:11])=[O:6])([CH3:3])[CH3:2]참가 물질
5
실험 절차
A mixture of isopropoxycarbonyloxyethyl chloride (=2-chloroethyl isopropylcarbonate) (1.67 g), carbon tetrachloride (10 ml), sodium iodide (2.10 g) and anhydrous zinc chloride (0.08 g) is stirred at room temperature for 2 hours, and thereafter, ice water is added to the mixture. The organic layer is separated, and the aqueous layer is extracted twice.with carbon tetrachloride. The combined organic layers are washed, dried and evaporated under reduced pressure to give isopropoxycarbonyloxyethyl iodide (=2-iodoethyl isopropylcarbonate) (1.48 g) as an oil.
후처리
- customThe organic layer is separated
- extractionthe aqueous layer is extracted twice.with carbon tetrachloride
- washThe combined organic layers are washed
- customdried
- customevaporated under reduced pressure
출처 및 근거
- ORD 기록
- ord-89e5832df91a4a02a5a9d6bf1742368b
- 출처 데이터셋
- uspto-grants-1993_05
- 특허 번호
- US05208348
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