1-Bromohexane → HCID 54034378, 화합물

HRID 248352노트

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HRID 248352 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6](/[CH:9]=[C:10](\[N+:22]#[C-:23])/[C:11](/[N+:20]#[C-:21])=[CH:12]/[C:13]2[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=2)=[CH:5][CH:4]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:30](Br)[CH2:31][CH2:32][CH2:33][CH2:34][CH3:35]>CN(C=O)C>[CH2:30]([O:19][C:16]1[CH:17]=[CH:18][C:13]([CH:12]=[C:11]([N+:20]#[C-:21])[C:10]([N+:22]#[C-:23])=[CH:9][C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=2)=[CH:14][CH:15]=1)[CH2:31][CH2:32][CH2:33][CH2:34][CH3:35]

참가 물질

5

반응물 3

HCID 81011-BromohexaneHCID 11430Potassium CarbonateHCID 6441021xanthocillin X monomethyl ether

생성물 1

HCID 54034378HCID 54034378, 화합물수율 94%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

13 mg of xanthocillin X monomethyl ether was dissolved in 2 ml of DMF and 40 mg of potassium carbonate was added thereto. Further, 50 μl of n-hexyl bromide was added thereto and the mixture thus formed was extracted with 30 ml portions of ethyl acetate thrice. The extracts were combined, successively washed with water and a saturated aqueous solution of sodium chloride and dried over sodium sulfate. The sodium sulfate was filtered off and the solvent was distilled from the filtrate. Thus 15 mg of 1-(4'-n-hexyloxyphenyl)-4-(4'-methoxyphenyl)-2,3-diisocyano-1,3-butadiene was obtained in the form of a brown solid. Yield: 94%.

후처리

  1. customthe mixture thus formed
  2. extractionwas extracted with 30 ml portions of ethyl acetate thrice
  3. washsuccessively washed with water
  4. dry with materiala saturated aqueous solution of sodium chloride and dried over sodium sulfate
  5. filtrationThe sodium sulfate was filtered off
  6. distillationthe solvent was distilled from the filtrate

출처 및 근거

ORD 기록
ord-7ae9a2fe3d7d477693aba126e9f970dd
출처 데이터셋
uspto-grants-1993_05
특허 번호
US05210097

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