Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Fluoroquinolonic acid → 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[3-(phenoxymethyl)-1-piperazinyl]-3-quinolinecarboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Fluoroquinolonic acid | HCID 483180 | — |
| 반응물 | 3-Phenoxymethylpiperazine | HCID 19763604 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[3-(phenoxymethyl)-1-piperazinyl]-3-quinolinecarboxylic acid | HCID 14839407 | — |
반응 단계
A 0.6 g portion of 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 1.23 g of 3-(phenoxymethyl)piperazine and 5 ml of pyridine were reacted as described in Example 81, giving 235 mg of the desired product, mp 112°-115° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05210193 |
| 출처 데이터셋 | uspto-grants-1993_05 |
| ORD ID | ord-60bd551670914408ab036a718445de43 |
| 출처 메모 | uspto-grants-1993_05 |