Carbon Dioxide → S-(alpha,beta-dicarboxyethyl)glutathione calcium

HRID 248802

반응식

HRID 248802 반응식
[C:1]([CH:4]([S:9][CH2:10][C@@H:11]([C:22]([NH:24][CH2:25][C:26]([OH:28])=[O:27])=[O:23])[NH:12][C:13](=[O:21])[CH2:14][CH2:15][C@@H:16]([C:18]([OH:20])=[O:19])[NH2:17])[CH2:5][C:6]([OH:8])=[O:7])([OH:3])=[O:2].C(=O)([O-])[O-].[Ca+2:33].C(=O)=O>O>[Ca:33].[C:1]([CH:4]([S:9][CH2:10][C@@H:11]([C:22]([NH:24][CH2:25][C:26]([OH:28])=[O:27])=[O:23])[NH:12][C:13](=[O:21])[CH2:14][CH2:15][C@@H:16]([C:18]([OH:20])=[O:19])[NH2:17])[CH2:5][C:6]([OH:8])=[O:7])([OH:3])=[O:2]

참가 물질

5

반응물 3

HCID 280Carbon DioxideHCID 10112Calcium CarbonateHCID 9802383S-(1,2-Dicarboxyethyl)glutathione

생성물 1

HCID 86746843S-(alpha,beta-dicarboxyethyl)glutathione calcium수율 100.5%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

In 40 ml of water is dissolved 2 g of S-(α,β-dicarboxyethyl)glutathione followed by addition of 1 g of calcium carbonate. The mixture is stirred under warming. When the evolution of carbon dioxide gas has ceased, the excess of calcium carbonate is filtered off and the filtrate is concentrated under reduced pressure. To the concentrate is added ethanol and the resulting white crystals are collected by filtration and recrystallized from water-ethanol. Thus is obtained 2.2 g of the title compound as white powdery crystals.

후처리

  1. temperatureunder warming
  2. filtrationthe excess of calcium carbonate is filtered off
  3. concentrationthe filtrate is concentrated under reduced pressure
  4. additionTo the concentrate is added ethanol
  5. filtrationthe resulting white crystals are collected by filtration
  6. customrecrystallized from water-ethanol

출처 및 근거

ORD 기록
ord-c2f5fdbeaf194800bb9fed483cfb3468
출처 데이터셋
uspto-grants-1993_05
특허 번호
US05212159

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