Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Pyridin-4-YL-acrylic acid methyl ester → Methyl 3-(4-pyridyl)propanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Pyridin-4-YL-acrylic acid methyl ester | HCID 98163 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Methyl 3-(4-pyridyl)propanoate | HCID 3704115 | — |
반응 단계
Methyl 3-(4-pyridinyl)propenoate (7.00 grams) and 10% palladium on carbon (1.00 gram) were vigorously stirred in methanol (70 mL) at room temperature under a hydrogen atmosphere for 5 hours. The catalyst was removed by filtration through a filter aide, and the filtrate was evaporated in vacuo. The crude product was purified by distillation in a kugelrohr apparatus. Yield: 5.14 grams (73%). Bp: 125° C. (oven temperature) at 0.6 mm Hg.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05212169 |
| 출처 데이터셋 | uspto-grants-1993_05 |
| ORD ID | ord-b069747be25c4f4e8fd7969622b7dc70 |
| 출처 메모 | uspto-grants-1993_05 |