Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methylanisole → 4-Bromo-1-methoxy-2-methylbenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methylanisole | HCID 33637 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 촉매 | Benzoyl Peroxide | HCID 7187 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 4-Bromo-1-methoxy-2-methylbenzene | HCID 608315 | 47.1% |
반응 단계
A solution of 24 g of 2-methylanisole, 35 g of N-bromosuccinimide and 1.24 g of dibenzoyl peroxide in 150 ml of carbon tetrachloride was heated to boiling under reflux for 12 hours. After cooling the solution was filtered and the filtrate is evaporated. The residue was recrystallized from hexane. There were obtained 18.6 g (47%) of 4-bromo-2-methylanisole as a colorless solid; m.p. 66°-68°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05214046 |
| 출처 데이터셋 | uspto-grants-1993_05 |
| ORD ID | ord-e726e1f3800646a79b1e16dd269c2994 |
| 출처 메모 | uspto-grants-1993_05 |