2-Chloro-5-(chloromethyl)pyridine → N-((2-Chlorothiazol-5-yl)methyl)ethanamine

HRID 249501

반응식

HRID 249501 반응식
[Cl:1][C:2]1[S:3][C:4]([CH2:7]Cl)=[CH:5][N:6]=1.ClC1[N:15]=[CH:14][C:13](CCl)=CC=1>C(Cl)Cl>[Cl:1][C:2]1[S:3][C:4]([CH2:7][NH:15][CH2:14][CH3:13])=[CH:5][N:6]=1

참가 물질

4

반응물 2

HCID 1554792-Chloro-5-(chloromethyl)pyridineHCID 27631792-Chloro-5-chloromethylthiazole

생성물 1

HCID 22450338N-((2-Chlorothiazol-5-yl)methyl)ethanamine

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

The reaction procedure of Reference Example 17 was repeated except that crude 2-chloro-5-chloromethylthiazole was used in lieu of 6-chloro-3-pyridylmethyl chloride and that CH2Cl2 was used as the extractant. The procedure gave the title compound as a crude oil.

후처리

  1. customThe reaction procedure of Reference Example 17

출처 및 근거

ORD 기록
ord-eef47cd986ac4f6abf30eb8c55e6c572
출처 데이터셋
uspto-grants-1993_05
특허 번호
US05214152

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