Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Nitrobenzenesulfonyl chloride → N,N-dimethyl-4-nitrobenzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Nitrobenzenesulfonyl chloride | HCID 7404 | — |
| 반응물 | Dimethylamine, hydrochloride | HCID 10473 | — |
| 반응물 | N,N-Diisopropylmethylamine | HCID 547370 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N,N-dimethyl-4-nitrobenzenesulfonamide | HCID 2747580 | — |
반응 단계
4.43 g (20 mmol) of 4-nitrobenzenesulphonic acid chloride are added dropwise at 0° C. to a solution of 2.45 g (30 mmol) of dimethylamine-hydrochloride and 6.46 g (50 mmol) of N,N-diisopropyl-N-methylamine in 30 ml of dichloromethane. The mixture is stirred for 18 hours at ambient temperature. Then the reaction solution is washed with water and dilute hydrochloric acid, dried over magnesium sulphate and evaporated to dryness.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06855710B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-fa275b5c963c420186aa69e2eb377b96 |
| 출처 메모 | uspto-grants-2005_02 |