Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → 2-Phenylbutyryl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | 2-Phenylbutyric Acid | HCID 7012 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Phenylbutyryl chloride | HCID 98173 | 68% |
반응 단계
Thionyl chloride (0.12 mol) in 60 mL of CH2Cl2 was added to a stirred solution of 2-phenylbutyric acid (16.4 g, 0.10 mol). A catalytic amount of DMF was added and the reaction was allowed to continue overnight at room temperature. The volatiles were removed under vacuum and the residual liquid was vacuum distilled to yield 12.4 g (68%) of 2-phenylbutyryl chloride. IR (neat) 1798 cm-1 (C=O).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05214191 |
| 출처 데이터셋 | uspto-grants-1993_05 |
| ORD ID | ord-27d8209bcb5d425b9dd1ab8a3f96bc9c |
| 출처 메모 | uspto-grants-1993_05 |