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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 249673생성일: 2026년 10월 25일

Ethyl 4-Chloroquinoline-3-carboxylate → Ethyl 4-chloro-6-fluoroquinoline-3-carboxylate

https://huagongshe.com/reaction/249673

반응식

참여 물질

역할이름HCID투입량
반응물Ethyl 4-Chloroquinoline-3-carboxylateHCID 268963—
반응물HCID 178469553HCID 178469553—
생성물Ethyl 4-chloro-6-fluoroquinoline-3-carboxylateHCID 1479088—

반응 단계

The title compound was prepared following the procedure described in Step 2 for the synthesis of 3a using 2b instead of 2a. 1H NMR (CDCl3) δ (ppm): 1.47 (3H, t, J=7.08 Hz), 4.51 (2H, q, J=7.08 Hz), 7.63 (1H, m), 8.02 (1H, dd, J=9.52, 2.68 Hz), 8.15 (1H, dd, J=9.27, 5.37 Hz), 9.15 (1H, s). m/z 254.6 (MH+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07863266B2
출처 데이터셋uspto-grants-2011_01
ORD IDord-d4f34c16031c47b7b516f9ebb1546ff4
출처 메모uspto-grants-2011_01