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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 249837생성일: 2026년 10월 26일

(3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride → (S)-N-(quinuclidine-8-yl)-2-(3-phenylmorpholino)benzoxazole-4-carboxamide

https://huagongshe.com/reaction/249837

반응식

참여 물질

역할이름HCID투입량
반응물(3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochlorideHCID 12494973—
반응물2-(3-Phenylmorpholino)benzoxazole-4-carboxylic acidHCID 66873991—
생성물(S)-N-(quinuclidine-8-yl)-2-(3-phenylmorpholino)benzoxazole-4-carboxamideHCID 66873796—

반응 단계

Following general procedure GP-C1, a mixture of 2-(3-phenylmorpholino)benzoxazole-4-carboxylic acid and (S)-(−)-3-aminoquinuclidine dihydrochloride were coupled to provide (S)—N-(quinuclidine-8-yl)-2-(3-phenylmorpholino)benzoxazole-4-carboxamide which was converted to the hydrochloride salt following general procedure GP-D1. 1H NMR and MS consistent.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07863271B2
출처 데이터셋uspto-grants-2011_01
ORD IDord-f5d75d2ffe4c497b88d7a0603fee1245
출처 메모uspto-grants-2011_01