2-amino-N,N-dimethylacetamide → Methyl 2-(2-(dimethylamino)-2-oxoethylamino)benzoxazole-4-carboxylate

반응식

Cl[C:2]1[O:3][C:4]2[C:5](=[C:7]([C:11]([O:13][CH3:14])=[O:12])[CH:8]=[CH:9][CH:10]=2)[N:6]=1.[NH2:15][CH2:16][C:17]([N:19]([CH3:21])[CH3:20])=[O:18]>>[CH3:20][N:19]([CH3:21])[C:17](=[O:18])[CH2:16][NH:15][C:2]1[O:3][C:4]2[C:5](=[C:7]([C:11]([O:13][CH3:14])=[O:12])[CH:8]=[CH:9][CH:10]=2)[N:6]=1

참가 물질

반응물 2

HCID 49618232-amino-N,N-dimethylacetamide

HCID 56924368Methyl 2-chlorobenzo[d]oxazole-4-carboxylate

생성물 1

HCID 66874290Methyl 2-(2-(dimethylamino)-2-oxoethylamino)benzoxazole-4-carboxylate

실험 절차

Following general procedure GP-A, a mixture of methyl 2-chlorobenzoxazole-4-carboxylate and 2-amino-N,N-dimethylacetamide provided methyl 2-(2-(dimethylamino)-2-oxoethylamino)benzoxazole-4-carboxylate. 1H NMR and MS consistent.

출처 및 근거

ORD 기록: ord-7bd4de750e1f474eb587f335e1e9215e
출처 데이터셋: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07863271B2

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