Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Chloro-4-hydroxyisoquinoline-3-carboxylic acid → (S)-2-[(1-Chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]-3-hydroxy-propionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Chloro-4-hydroxyisoquinoline-3-carboxylic acid | HCID 11020520 | — |
| 반응물 | H-Ser(tBu)-OtBu HCl | HCID 16211506 | — |
| 생성물 | (S)-2-[(1-Chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]-3-hydroxy-propionic acid | HCID 86595449 | — |
반응 단계
Prepared in analogy to Example A-2 e) and f) from 1-chloro-4-hydroxy-isoquinoline-3-carboxylic acid from Example A-2 d) and (S)-2-amino-3-tert-butoxy-propionic acid tert-butyl ester hydrochloride; MS-(+)-ion: M+1=310.9 amu.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07863292B2 |
| 출처 데이터셋 | uspto-grants-2011_01 |
| ORD ID | ord-882e7a22a1244df28bf46686d44a5926 |
| 출처 메모 | uspto-grants-2011_01 |