Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl D-alaninate hydrochloride → (R)-2-[(7-Isopropoxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]propionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl D-alaninate hydrochloride | HCID 11182647 | — |
| 반응물 | 1-Chloro-4-hydroxy-7-isopropoxy-isoquinoline-3-carboxylic acid | HCID 53870439 | — |
| 생성물 | (R)-2-[(7-Isopropoxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]propionic acid | HCID 86595460 | — |
반응 단계
Analogously to Example A-56, 0.040 g of 7-isopropoxy-1-chloro-4-hydroxy-isoquinoline-3-carboxylic acid were allowed to react with D-Alanine methyl ester hydrochloride. The intermediate ester product was hydrolyzed as in Example A-56 to give 0.042 g of a white solid: MS-(−)-ion, M−1=353.0 amu.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07863292B2 |
| 출처 데이터셋 | uspto-grants-2011_01 |
| ORD ID | ord-29e4ce0491cf45cca2f91a7175ab0542 |
| 출처 메모 | uspto-grants-2011_01 |