Thionyl Chloride → HCID 58087452, 화합물

반응식

[CH2:1]([S:4]([NH:7][C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11](O)=[O:12])(=[O:6])=[O:5])[CH2:2][CH3:3].S(Cl)([Cl:19])=O>>[CH2:1]([S:4]([NH:7][C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11]([Cl:19])=[O:12])(=[O:6])=[O:5])[CH2:2][CH3:3]

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 162282623-(Propane-1-sulfonamido)benzoic acid

생성물 1

HCID 58087452HCID 58087452, 화합물

실험 절차

A solution of 3-(propane-1-sulfonylamino)-benzoic acid (76, 1.20 g, 4.93 mmol) in thionyl chloride was heated to reflux for 3.0 hours. Evaporation of the solvent gave compound 77 as white solid that was used for the next step.

후처리

temperatureto reflux for 3.0 hours
customEvaporation of the solvent

출처 및 근거

ORD 기록: ord-5e4920dd7bd545bf8e68f5ef11f5b345
출처 데이터셋: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07863288B2

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