Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(Pyridin-2-yl)ethan-1-amine → N-((3-Methylpyridin-2-yl)methyl)-1-(pyridin-2-yl)ethanamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(Pyridin-2-yl)ethan-1-amine | HCID 541877 | — |
| 반응물 | 3-Methylpyridine-2-carboxaldehyde | HCID 1501874 | — |
| 반응물 | Sodium triacetoxyborohydride | HCID 5049666 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-((3-Methylpyridin-2-yl)methyl)-1-(pyridin-2-yl)ethanamine | HCID 45098009 | — |
반응 단계
Using General Procedure B: Reaction of 3-methyl-pyridine-2-carbaldehyde in CH2Cl2 and 1-pyridin-2-yl-ethylamine with NaBH(OAc)3 gave (3-methyl-pyridin-2-ylmethyl)-(1-pyridin-2-yl-ethyl)-amine as a pale yellow oil. 1H NMR (CDCl3) 1.48 (d, 3H, J=6.9 Hz), 2.19 (s, 3H), 3.70-3.83 (m, 2H), 4.02 (q, 1H, J=6.9 Hz), 7.06 (dd, 1H, J=5.4, 7.5 Hz), 7.13-7.18 (m, 1H), 7.36-7.40 (m, 1H), 7.47 (d, 1H, J=7.8 Hz), 7.66 (dt, 1H, J=1.8, 7.8 Hz), 8.40 (d, 1H, J=3.9 Hz), 8.55-8.57 (m, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07863293B2 |
| 출처 데이터셋 | uspto-grants-2011_01 |
| ORD ID | ord-ce1554d19c9c4595bf00cdc044d5a4bc |
| 출처 메모 | uspto-grants-2011_01 |