Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(Pyridin-2-yl)ethan-1-amine → (1-pyridin-2-yl-ethyl)-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-benzimidazol-2-ylmethyl]-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(Pyridin-2-yl)ethan-1-amine | HCID 541877 | — |
| 반응물 | Sodium triacetoxyborohydride | HCID 5049666 | — |
| 반응물 | 1-(2-Trimethylsilylethoxymethyl)-2-formyl-benzimidazole | HCID 12017128 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | (1-pyridin-2-yl-ethyl)-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-benzimidazol-2-ylmethyl]-amine | HCID 67272285 | — |
반응 단계
Using General Procedure B: Reaction of 1-(2-trimethylsilanyl-ethoxymethyl)-1H-benzimidazole-2-carbaldehyde in CH2Cl2 with 1-pyridin-2-yl-ethylamine and NaBH(OAc)3 gave (1-pyridin-2-yl-ethyl)-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-benzimidazol-2-ylmethyl]-amine as a pale green oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07863293B2 |
| 출처 데이터셋 | uspto-grants-2011_01 |
| ORD ID | ord-1f8133d42d5c479486c641bc7797bf4e |
| 출처 메모 | uspto-grants-2011_01 |