참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methanimidamide, N,N-diphenyl- | HCID 78296 | — |
| 반응물 | 3-(3-Methoxyphenyl)-3-oxopropanenitrile | HCID 584716 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 2-(3-Methoxybenzoyl)-3-phenylamino-acrylonitrile | HCID 67024286 | — |
반응 단계
A solution of 3-methoxybenzoylacetonitrile (1.20 g, 68.5 mmol, 1.0 eq) and diphenylformamidine (1.34 g, 68.5 mmol, 1.0 eq) in 25 mL of toluene was stirred at room temperature for 2h then heated to 100° C. overnight. The solution was cooled and diluted with hexanes. The resulting solid was filtered and dried to provide the desired product. HPLC (4 minute 10-90 gradient) tR 3.05 min; MS m/z 279.2 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07863314B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_01 |
|---|
| ORD ID | ord-6dd22fdfc3474aa3af65bf73b381ac40 |
|---|
| 출처 메모 | uspto-grants-2011_01 |
|---|
