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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2515생성일: 2026년 10월 24일

2,5-Dimethoxytetrahydrofuran → 4-(Pyrrole-1-yl)-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(3-methoxyphenyl)benzamide

https://huagongshe.com/ko/reaction/2515

반응식

참여 물질

역할이름HCID투입량
반응물2,5-DimethoxytetrahydrofuranHCID 79098—
반응물4-amino-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(3-methoxyphenyl)benzamideHCID 19689881—
생성물4-(Pyrrole-1-yl)-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(3-methoxyphenyl)benzamideHCID 1968993378%

반응 단계

Using 4-amino-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(3-methoxyphenyl)benzamide (238.1 mg, 0.50 mmol) and 2,5-dimethoxytetrahydrofuran (0.066 ml, 0.50 mmol), the procedure of Inventive Example 149 was repeated to obtain 205.0 mg (78.0%) of the title compound in a light brown amorphous form.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05728835
출처 데이터셋uspto-grants-1998_03
ORD IDord-a87ab204e6184d2c93e710080ffacda1
출처 메모uspto-grants-1998_03