참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | 1-(4-Iodophenyl)ethan-1-one | HCID 72869 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-Bromo-1-(4-iodophenyl)ethanone | HCID 256572 | 102.6% |
반응 단계
Dissolving 20 g (81 mmol) of 4′-iodo acetophenone into 200 milliliter of acetic acid, and adding 12.8 g (81 mmol) of bromine while cooling with ice, stirred at the temperature of 15° C. for 3 hours. After the color of bromine disappeared, adding water and separating the precipitated solids by filtration, thereby obtained 27 g of crude 2-bromo-4′-iodo acetophenone.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07867629B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_01 |
|---|
| ORD ID | ord-4f186ab3782a4e79825b256306f12e77 |
|---|
| 출처 메모 | uspto-grants-2011_01 |
|---|
