Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 3-(2-Bromoacetyl)benzonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | 3-Acetylbenzonitrile | HCID 80222 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 3-(2-Bromoacetyl)benzonitrile | HCID 2735867 | — |
반응 단계
Br2 (1 mmol) was dropwise added to a solution of 3-acetylbenzonitrile (1 mmol) in Et2O (15 ml) at 0° C., and then the mixture was stirred at r.t. for 4 h. Water was added, and the mixture was extracted with EtOAc. The organic layer was dried over Na2SO4, and was concentrated to give an oil, i.e., 3-(2-bromoacetyl)benzonitrile, which was directly used for the next step without purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07868001B2 |
| 출처 데이터셋 | uspto-grants-2011_01 |
| ORD ID | ord-bc195a55eb7041ccb0c4ce7b56ac6d09 |
| 출처 메모 | uspto-grants-2011_01 |