Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → 2-Amino-5-chloro-3-methoxybenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Chlorosuccinimide | HCID 31398 | — |
| 반응물 | 2-Amino-3-methoxybenzoic acid | HCID 255720 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-Amino-5-chloro-3-methoxybenzoic acid | HCID 54595874 | 61.1% |
반응 단계
To a mixture of 1.67 g of 2-amino-3-methoxybenzoic acid and 100 ml of N,N-dimethylformamide was added 1.3 g of N-chlorosuccinimide at room temperature, and the resulting mixture was stirred at room temperature for 10 hours. Water was poured into the reaction mixture, and a deposited precipitate was collected by filtration to obtain 1.2 g of 2-amino-5-chloro-3-methoxybenzoic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07867949B2 |
| 출처 데이터셋 | uspto-grants-2011_01 |
| ORD ID | ord-07d6ef35f3d041359215050c38ce936e |
| 출처 메모 | uspto-grants-2011_01 |