Bromine → 3-Amino-7-bromo-4-chloro-2-naphthoic acid
반응식
[NH2:1][C:2]1[C:3]([C:13]([OH:15])=[O:14])=[CH:4][C:5]2[C:10]([C:11]=1[Cl:12])=[CH:9][CH:8]=[CH:7][CH:6]=2.[Br:16]Br>C(O)(=O)C>[NH2:1][C:2]1[C:3]([C:13]([OH:15])=[O:14])=[CH:4][C:5]2[C:10]([C:11]=1[Cl:12])=[CH:9][CH:8]=[C:7]([Br:16])[CH:6]=2참가 물질
4
실험 절차
To a mixture of 0.56 g of 3-amino-4-chloro-2-naphthoic acid and 20 ml of acetic acid was added dropwise 0.4 g of bromine at room temperature. The resulting mixture was stirred at room temperature for 1 hour. A deposited precipitate was collected by filtration, and the resulting solid was washed successively with acetic acid and ethyl acetate to obtain 0.36 g of 3-amino-7-bromo-4-chloro-2-naphthoic acid of the formula:
후처리
- filtrationA deposited precipitate was collected by filtration
- washthe resulting solid was washed successively with acetic acid and ethyl acetate
출처 및 근거
- ORD 기록
- ord-9e240e6e4ec245ffaaf47f89008ea9f9
- 출처 데이터셋
- uspto-grants-2011_01
- 특허 번호
- US07867949B2
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