Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → 4-Benzoylamino-N-[2-(4-benzoylpiperidino)ethyl]-N-(3-pyridyl)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | Benzoyl chloride | HCID 7412 | — |
| 반응물 | 5-HT2A antagonist 1 | HCID 9888832 | — |
| 생성물 | 4-Benzoylamino-N-[2-(4-benzoylpiperidino)ethyl]-N-(3-pyridyl)benzamide | HCID 19689888 | 85.9% |
반응 단계
Using 4-amino-N-[2-(4-benzoylpiperidino)ethyl]-N-(3-pyridyl)benzamide (210.7 mg, 0.49 mmol), benzoyl chloride (0.07 ml, 0.60 mmol) and pyridine (0.05 ml, 0.62 mmol), the procedure of Inventive Example 165 was repeated to obtain 224.3 mg (85.9%) of the title compound in a colorless powder form.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05728835 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-df4b0db0bdde491cb5906e69e4e16de2 |
| 출처 메모 | uspto-grants-1998_03 |