참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Pyridinium chloride | HCID 10176127 | — |
| 반응물 | 6-Methoxy-1-benzothiophene | HCID 13634237 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Benzo(b)thiophene-6-ol | HCID 88004 | 98.5% |
반응 단계
6-Methoxybenzo[b]thiophene (6.15 g, 37.45 mmol) and pyridine hydrochloride (18.5 g) were heated together at 210° C. for 1 h. The mixture was cooled to 100° C., diluted with water (125 mL) and extracted with dichloromethane (3×70 mL). The combined extracts were washed with water (125 mL), dried (MgSO4) and evaporated in vacuo to give the title compound (5.54 g, 98%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07868017B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_01 |
|---|
| ORD ID | ord-5e1e09f2b3994491a6902c43b3fe3a66 |
|---|
| 출처 메모 | uspto-grants-2011_01 |
|---|
