Methyl 4-methoxybutanoate → HCID 66888453, 화합물

반응식

[Br:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][NH2:9])=[N:6][CH:7]=1.[CH3:10][O:11][CH2:12][CH2:13][CH2:14][C:15](OC)=O>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]([C:15]([CH2:14][CH2:13][CH2:12][O:11][CH3:10])=[N:9][N:8]=2)[CH:7]=1

참가 물질

반응물 2

HCID 542317Methyl 4-methoxybutanoate

HCID 115356995-Bromo-2-hydrazinopyridine

생성물 1

HCID 66888453HCID 66888453, 화합물

실험 절차

A mixture of 18.80 g of (5-bromopyridin-2-yl)hydrazine [77992-44-0] and 14.54 g of methyl 4-methoxybutyrate [29006-01-7] is heated to reflux over 16 hours. The reaction solution is subsequently cooled and purified by means of flash chromatography (SiO2 60F). The title compound is identified on the basis of the Rf value.

후처리

temperatureis heated
temperatureto reflux over 16 hours
temperatureThe reaction solution is subsequently cooled
custompurified by means of flash chromatography (SiO2 60F)

출처 및 근거

ORD 기록: ord-5ff049fd4acc42c1a6ba190671a246db
출처 데이터셋: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07868036B2

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