Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 1-(2-Amino-3-nitrophenoxy)-2,3-epoxypropane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Glycidyl tosylate | HCID 160868 | — |
| 반응물 | 2-Amino-3-Nitrophenol | HCID 4115495 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 1-(2-Amino-3-nitrophenoxy)-2,3-epoxypropane | HCID 11344838 | — |
반응 단계
21.7 g (0.095 mol) of glycidyl tosylate, 10 g (0.0475 mol) of 2-amino-3-nitrophenol and 6.5 g of crushed K2CO3 are mixed in acetone and the mixture is heated at reflux for 18 hours. The mixture is filtered and the solvent is evaporated under reduced pressure. The crude reaction product is purified by flash chromatography, elution being carried out with a 9/1 hexane/ethyl acetate mixture. The title compound is obtained. M.p.: 7°-78° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06858629B1 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-e07988679b094e7aa963e37ef2a90aed |
| 출처 메모 | uspto-grants-2005_02 |