Glycine → N-Dodecamidoglycine

참여 물질

역할	이름	HCID	투입량
반응물	Glycine	HCID 750	—
반응물	Dimethylformamide	HCID 6228	—
반응물	Dodecane, 1-isocyanato-	HCID 77873	—
반응물	Diisopropylethylamine	HCID 81531	—
용매	Water	HCID 962	—
용매	Tetrahydrofuran	HCID 8028	—
생성물	N-Dodecamidoglycine	HCID 86599604	—

반응 단계

Glycine (0.40 g, 5.25 mmol) and 0.91 mL of diisopropylethylamine (5.25 mmol) were dissolved in 4 mL DMF and 6 mL water. Dodecylisocyanate (0.72 mL, 3.0 mmol) in 7 mL tetrahydrofuran was added and the mixture was stirred for 1 h at room temperature. Water (40 mL) was added and the resulting mixture was washed with ethyl acetate twice. The aqueous layer was acidified with 6N HCl, the resulting precipitate was filtered, and then dried to provide 575 mg of the title compound.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07868135B2
출처 데이터셋	uspto-grants-2011_01
ORD ID	ord-107a21eddf7c429fa48da28ebabfc9ee
출처 메모	uspto-grants-2011_01