Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,3-Dihydroxybutanedioic Acid → 4-Acetylamino-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(3-methoxyphenyl)benzamide tartarate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,3-Dihydroxybutanedioic Acid | HCID 875 | — |
| 반응물 | 4-Acetylamino-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(3-methoxyphenyl)benzamide | HCID 19689904 | — |
| 생성물 | 4-Acetylamino-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(3-methoxyphenyl)benzamide tartarate | HCID 19690058 | 75.3% |
반응 단계
Using 4-acetylamino-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(3-methoxyphenyl)benzamide (155.0 mg, 0.30 mmol) and tartaric acid (35.0 mg, 0.30 mmol), the procedure of Inventive Example 211 was repeated to obtain 143.0 mg (75.3%) of the title compound in a colorless powder form.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05728835 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-f8098aa2891d4fcea8abf7e7fa4e55c8 |
| 출처 메모 | uspto-grants-1998_03 |