Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 5-Fluoro-2-(4'-acetamido-3'-methylphenyl)benzothiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Acetyl chloride | HCID 6367 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 4-(5-Fluoro-1,3-benzothiazol-2-yl)-2-methylaniline | HCID 396813 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 5-Fluoro-2-(4'-acetamido-3'-methylphenyl)benzothiazole | HCID 9882781 | — |
반응 단계
Acetyl Chloride (0.09g, 1.55 mmol) was added to a solution of 5-fluoro2-(4′-amino-3′-methylphenyl)benzothiazole (0.2 g, 0.78 mmol) in chloroform (5 ml) containing triethylamine (86 mg, 0.85 mmol). The resulting solution was stirred for 30 min, then poured into water (20 ml). The organic layer was removed, dried (Na2SO4) and evaporated. Recrystallisation from ethanol gave a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06858633B1 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-ae5991969bc04edba7258ddf1b0edf6e |
| 출처 메모 | uspto-grants-2005_02 |