2-Aminothiazole → phenyl N-(1,3-thiazol-2-yl)carbamate

HRID 252722노트

반응식

HRID 252722 반응식
[NH2:1][C:2]1[S:3][CH:4]=[CH:5][N:6]=1.Cl[C:8]([O:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:9]>>[S:3]1[CH:4]=[CH:5][N:6]=[C:2]1[NH:1][C:8](=[O:9])[O:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

참가 물질

3

반응물 2

HCID 21552-AminothiazoleHCID 15891Phenyl chloroformate

생성물 1

HCID 651148phenyl N-(1,3-thiazol-2-yl)carbamate

실험 절차

Using analogous procedures to those described in Example 49, the appropriate 2-amino-1,3-thiazole was reacted with phenyl chloroformate and the phenyl N-(1,3-thiazol-2-yl)carbamate so obtained was reacted with the appropriate alkylamine to give the compounds described in Table II.

출처 및 근거

ORD 기록
ord-e48e550cbcf34822bef06c9844b018ff
출처 데이터셋
uspto-grants-2011_01
특허 번호
US07868188B2

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