Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Bicarbonate → HCID 178497918, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 반응물 | Methyl 4-(aminomethyl)benzoate hydrochloride | HCID 2729253 | — |
| 반응물 | 2,6-dichloro-1H-purine | HCID 178418875 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | HCID 178497918 | HCID 178497918 | 60% |
반응 단계
A suspension of 2,6-dichloro-9H-purine (1 g, 5.29 mmol), 4-aminomethyl-benzoic acid methyl ester hydrochloride (1.2 equiv., 1.28 g) and NaHCO3 (2.1 equiv., 935 mg, in water was heated at 100° C. The homogeneous solution thus formed was refluxed 30 min. The resulting white precipitate was filtered, washed with cold water and dried under vacuum giving the title compound 241 (1 g, 3.14 mmol, 60%). LRMS calc: 317.7. found: 318.3 (MH)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07868204B2 |
| 출처 데이터셋 | uspto-grants-2011_01 |
| ORD ID | ord-cd092192b3494a3dbb0d3d6ea9f8cd5a |
| 출처 메모 | uspto-grants-2011_01 |